Literature Review: Adolescent Idiopathic Scoliosis

Puja Rizkina Angelita

doi:10.36312/biocaster.v5i3.538

Authors

Puja Rizkina Angelita Program Studi Pendidikan Dokter, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Mataram, Jalan Majapahit Nomor 62, Mataram, Nusa Tenggara Barat 83115, Indonesia

DOI:

https://doi.org/10.36312/biocaster.v5i3.538

Keywords:

Adolescent Idiopathic Scoliosis, Deformity, Early Detection, Adolescent Bones

Abstract

Adolescent Idiopathic Scoliosis (AIS) is the most common spinal deformity seen by general practitioners, pediatricians, and spine surgeons in adolescents aged 10–18 years. Also known as “late-onset” scoliosis, AIS is typically characterized by a lateral curvature of the spine of ≥10° on radiological examination. This article aims to examine the characteristics, prevalence, diagnostic methods, and risk factors of AIS through a literature review. The method used was a literature review of several scientific articles from the PubMed, Scopus, and Google Scholar databases published within the past 10 years. The results of the study indicate that AIS is more common in females, with a global prevalence ranging from 0.47 to 5.2%. Physical examinations, such as the Adams forward bend test, are common initial screening methods for detecting postural abnormalities, such as rib hump or shoulder asymmetry. The conclusions of this review emphasize the importance of early detection of AIS to prevent progression of the disorder and long-term biomechanical complications.

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References

Addai, D., Zarkos, J., & Bowey, A. J. (2020). Current Concepts in the Diagnosis and Management of Adolescent Idiopathic Scoliosis. Child’s Nervous System, 36(1), 1111-1119. https://doi.org/10.1007/s00381-020-04608-4

Aulia, T. N., Djufri, D., Gatam, L., & Yaman, A. (2023). Etiopathogenesis of Adolescent Idiopathic Scoliosis (AIS): Role of Genetic and Environmental Factors. Narra Journal, 3(3), 1-10. https://doi.org/10.52225/narra.v3i3.217

Az-zahra, F. K., Fadila, A., Zahira, L. A. F., Firdaus, A. A. D. C., Fadlurrohman, M. Z., Anindya, M. N. A., Aryuni, B. A., Vaidika, I. K. S., Ramadhita, N. I. S., Putra, R. A. J., Akbar, R. A., & Alaydrus, M. M. (2024). Adolescent Idiopatic Scoliosis: A Literatur Review. Jurnal Biologi Tropis, 24(1), 121-130. https://doi.org/10.29303/jbt.v24i1b.7961

Burwell, R. G., Clark, E. M., Dangerfield, P. H., & Moulton, A. (2016). Adolescent Idiopathic Scoliosis (AIS): A Multifactorial Cascade Concept for Pathogenesis and Embryonic Origin. Scoliosis and Spinal Disorders, 11(8), 1-7. https://doi.org/10.1186/s13013-016-0063-1

Herdea, A., Charkaoui, A., & Ulici, A. (2020). Prevalence of 25‑OH‑Vitamin D and Calcium Deficiency in Adolescent Idiopathic Scoliosis. Journal of Medicine and Life, 13(2), 260-264. https://doi.org/10.25122/jml-2020-0101

Jinnah, A. H., Lynch, K. A., Wood, T. R., & Hughes, M. S. (2025). Adolescent Idiopathic Scoliosis: Advances in Diagnosis and Management. Current Reviews in Musculoskeletal Medicine, 18(1), 54-60. https://doi.org/10.1007/s12178-024-09939-2

Kaelin, A. J. (2020). Adolescent Idiopathic Scoliosis: Indications for Bracing and Conservative Treatments. Annals of Translational Medicine, 8(1), 28-38. https://doi.org/10.21037/atm.2019.09.69

Kikanloo, S. R., Tarpada, S. P., & Cho, W. (2019). Etiology of Adolescent Idiopathic Scoliosis: A Literature Review. Asian Spine Journal, 13(3), 519-526. https://doi.org/10.31616/asj.2018.0096

Kusumi, K., & Dunwoodie, S. L. (2018). The Genetics and Development of Scoliosis. 2nd ed. Cham: Springer International Publishing.

Kuznia, A. L., Hernandez, A. K., & Lee, L. U. (2020). Adolescent Idiopathic Scoliosis: Common Questions and Answers. American Family Physician, 101(1), 19-23.

Latalski, M., Bromberek, A. D., Fatyga, M., Latalska, M., Kröber, M., & Zwolak, P. (2017). Current Insights into the Aetiology of Adolescent Idiopathic Scoliosis. Archives of Orthopaedic and Trauma Surgery, 137(10), 1327-1333. https://doi.org/10.1007/s00402-017-2756-1

Newton, P. O., Samdani, A. F., Shufflebarger, H. L., Betz, R. R., & Harms, J. (2021). Idiopathic Scoliosis: The Harms Study Group Treatment Guide (2nd ed.). New York: Thieme Medical Publishers.

Peng, Y., Wang, S. R., Qiu, G. X., Zhang, J. G., & Zhuang, Q. Y. (2020). Research Progress on the Etiology and Pathogenesis of Adolescent Idiopathic Scoliosis. Chinese Medical Journal, 133(4), 483-493. https://doi.org/10.1097/CM9.0000000000000652

Safnowandi, S. (2022). Pemanfaatan Vitamin C Alami sebagai Antioksidan pada Tubuh Manusia. Biocaster : Jurnal Kajian Biologi, 2(1), 1-8. https://doi.org/10.36312/bjkb.v2i1.43

Shanmuganathan, R., Sukumaran, S. V. A. K., & Shetty, A.P. (2020). Etiology and Natural History of Adolescent Idiopathic Scoliosis. Indian Spine Journal, 3(2), 131-142. https://doi.org/10.4103/isj.isj_62_19

St-Georges, M., Teles, A. R., Rabau, O., Saran, N., Ouellet, J. A., & Ferland, C. E. (2020). Adolescent Idiopathic Scoliosis: Evaluating Perioperative Back Pain through a Simultaneous Morphological and Biomechanical Approach. BMC Musculoskeletal Disorders, 21(1), 1-11. https://doi.org/10.1186/s12891-020-03462-4

Tetik, Y., Atıç, R., Ulus, S. A., Özkul, E., Yiğit, Ş., & Aydın, A. (2024). Evaluation of Adolescents with Idiopathic Scoliosis Treated with Posterior Spinal Fusion. Journal of Turkish Spinal Surgery, 35(3), 106-112. https://doi.org/10.4274/jtss.galenos.2024.60362

Thomas, J. J., Stans, A. A., Milbrandt, T. A., Kremers, H. M., Shaughnessy, W. J., & Larson, A. N. (2021). Trends in Incidence of Adolescent Idiopathic Scoliosis: A Modern US Population-based Study. Journal of pediatric orthopedics, 41(6), 327-332. https://doi.org/10.1097/BPO.0000000000001808

Wang, X., Yue, M., Cheung, J. P. Y., Cheung, P. W. H., Fan, Y., Wu, M., Wang, X., Zhao, S., Khanshour, A. M., Rios, J. J., Chen, Z., Wang, X., Tu, W., Chan, D., Yuan, Q., Qin, D., Qiu, G., Wu, Z., Zhang, T. J., Ikegawa, S., Wu, N., Wise, C. A., Hu, Y., Luk, K. D. K., Song, Y. Q., & Gao, B. (2024). Impaired Glycine Neurotransmission Causes Adolescent Idiopathic Scoliosis. Journal of Clinical Investigation, 134(2), 1-15. https://doi.org/10.1172/JCI168783